Search on: PEROXISOMAL BIFUNCTIONAL ENZYME 
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Descriptor English:   Peroxisomal Bifunctional Enzyme 
Descriptor Spanish:   Enzima Bifuncional Peroxisomal 
Descriptor Portuguese:   Enzima Bifuncional do Peroxissomo 
Synonyms English:   Peroxisomal-Bifunctional Enzymes  
Tree Number:   D08.811.399.475.400.349.500
D08.811.520.241.300.250.750
D08.811.641.781
D08.811.682.047.820.150.207.500
Definition English:   A monomeric protein found in liver peroxisomes that contains two enzymatically active domains; an enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase domain, and an (S)-3-hydroxyacyl-CoA dehydrogenase domain. The enzyme is stereospecific with regards to how cis and trans double bonds are metabolized. It is complemented by PEROXISOMAL MULTIFUNCTIONAL PROTEIN-2, which has the opposite stereospecificity. 
History Note English:   2014 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   55271 
Unique Identifier:   D063994 

Occurrence in VHL:
 

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